Pharmacology of Troxerutin

Troxerutin is derived from the Japanese pagoda tree and has been widely used in Western medicine since the 1960s.Troxerutin is a medication used in the treatment of varicose veins and other disorders which cause blood to pool. It is in a class of medications known as flavonoids and works by repairing damage to capillaries and making them less susceptible to subsequent damage. http://www.ebiochem.com

It can inhibit platelet aggregation, prevent thrombosis, can cure the vascular injury induced by 5 serotonin or bradykinin, increase the capillary resistance, reduce the capillary permeability, prevent edema caused by the increasement of vascular permeability. It has the significant protective effect to acute ischemic brain injury.As the treatment of cerebral thrombosis or the sequela due from the cerebral embolism, such as the hemiplegia, aphasia and myocardial infarction syndrome, arteriosclerosis, central retinitis, phlebitis of thrombosis, varicose veins, edema caused by the vascular permeability rising. http://www.ebiochem.com

Treatment with troxerutin is administered in a two different phases. In the first phase of treatment, medication is injected either into a vein or a muscle. Alternatively, or sometimes additionally, a patient may be given an oral dose of troxerutin for two to four weeks. Dosing is usually higher at the beginning of treatment and then lowered to maintenance levels once symptoms improve. http://www.ebiochem.com

After initial treatment with injections or oral medication, patients may be given a topical treatment of troxerutin. The medication is usually suspended in a gel, which is spread on the affected area once or twice daily. This method of administration is quite effective in relieving the symptoms of varicose veins and in reversing the damage to the blood vessels that is caused by the condition. http://www.ebiochem.com

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