Shellfish is a traditional remedy for arthritis. The indigenous Maori population of New Zealand uses Perna canaliculus, commonly known as the green-lipped mussel, for this purpose, as explained by Drugs.com. The website notes that some studies support the effectiveness of the New Zealand green-lipped mussel extract for treating inflammatory disorders such as arthritis and asthma. Standardized preparations of this supplement are available under the brand names Lyprinol and Seatone. The green-lipped mussel naturally contains omega-3 fatty acids, which help reduce inflammation, and chondroitin sulfate, a supplement used to decrease and prevent joint pain. Research is lacking on the safety of green-lipped mussel extract, according to the American Cancer Society, but the society notes that the substance appears to be “relatively non-toxic.”
Gastrointestinal Side Effects
A small number of people experience gastrointestinal effects when taking New Zealand green-lipped mussel and its extracts, according to Drugs.com. These side effects may include abdominal discomfort, gas, diarrhea and nausea.