An Overview of Resveratrol’s Medicinal Value

1)The effect of resveratrol to the proliferation of B16 melanocyte,the activity of cellular tyrosinase and the synthesis of melanin were investigated. The results showed that resveratrol can inhibit the cellular proliferation,reduce the activity of cellular tyrosinase,and obviously decreased the content of cellular melanin compared with arbutin and ethyl vitamin C,0.5 μg/mL resveratrol solution has the same effect with 50 μg/mL arbutin and ethyl Vc.

2)Resveratrol plays a role in protecting liver from damage by alcohol. Alcohol can cause liver damage in the form of steatosis or fatty liver, hepatitis, fibrosis and liver cirrhosis. In general, the amount and duration of alcohol abuse correlate with the presence and severity of liver damage, at least as regards the initial stage of fatty liver. After too much alcohol, Glutathione level will be low but after added resveratrol, this level returned soon.

3) Resveratrol is believed to stimulate the SiRT1 gene; this gene is the one that kicks in when a person begins to lose weight.This same phenomenon is believed to help slow the aging process. Taking resveratrol, then, can be a way to achieve anti-aging benefits without having to go on an extreme weight reduction diet. It is not surprising that so many people are making sure to include it in their regular, balanced diet.

4) Resveratrol, a nonflavonoid polyphenol naturally found in red wine and grapes, has been known to possess antioxidant, anticancer, and anti-inflammatory properties. From this study, rat primary midbrain neuron-glia cultures were used to elucidate the molecular mechanisms underlying resveratrol-mediated neuroprotection. The results clearly demonstrated that resveratrol protected DA neurons against lipopolysaccharide (LPS)-induced neurotoxicity in concentration- and time-dependent manners through the inhibition of microglial activation and the subsequent reduction of proinflammatory factor release. Mechanistically, resveratrol-mediated neuroprotection was attributed to the inhibition of NADPH oxidase. First, resveratrol reduced NADPH oxidase-mediated generation of reactive oxygen species. Second, LPS-induced translocation of NADPH oxidase cytosolic subunit p47 to the cell membrane was significantly attenuated by resveratrol. Third and most importantly, resveratrol failed to exhibit neuroprotection in cultures from NADPH oxidase-deficient mice. Furthermore, this neuroprotection was also related to an attenuation of the activation of mitogen-activated protein kinases and nuclear factor-kappaB signaling pathways in microglia. These findings suggest that resveratrol exerts neuroprotection against LPS-induced dopaminergic neurodegeneration, and NADPH oxidase may be a major player in resveratrol-mediated neuroprotection.

5) Research suggests that resveratrol can help control the symptoms of asthma and improve the effectiveness of corticosteroid drug treatment. Resveratrol has been shown to reduce asthmatic symptoms by regulating immune system responses and reducing inflammation.41 In addition, recent research on patients with chronic obstructive pulmonary disease (COPD) suggests that resveratrol could also help those asthmatics who do not respond well to corticosteroids because they are insensitive or resistant to them. Studies have shown that some 50% of people with asthma have some resistance to steroidal treatment.

What’s Muira Puama ?

Muira Puama in originated in Amazon of Brazil. Muira puama (also known as ‘potency wood’) is a small tree or bush that grows up to a height of 15 meters and produces petite white flowers having a pungent aroma akin to that of jasmine. The trunk of this shrub-like tree is grey, the leaves deep brown and it bears fruits that have an orange-yellow hue. Muira puama is indigenous to the Amazon rainforest in Brazil, where people have been employing the plant in the form of a stimulant for neuromuscular disorders, for baths and massage as well as an herbal tea to cure rheumatism, impotence and gastrointestinal problems.

In a French study involved 262 male patients shows that more than 62% patients changed their life by taking Muira Puama 1 g per day,while 51 per cent of patients suffering from erectile dysfunction were of the view that muira puama was helpful in improving their condition.The traditional purpose of taking Muira Puama is for commonly referred to as the “potency wood” because of its reported uses for stimulating the libido.Some people called Muira Puama as “Source of Strength”.

It is said that this herb is also beneficial to treating central nervous system disorder and it is also used as anti stress agent. Researches undertaken more recently showed that the extract from muira puama possessed adaptogenic (herbs that work to normalize the functioning of the systems of the body), anti-stress, and anti-fatigue properties as well as had positive and helpful effects on the central nervous system.

In 2003, Brazilian researchers have reported that an alcohol extract obtained from muira puama helped in retrieving memory in young as well as aged mice and documented that the extract may prove to be useful for patients enduring Alzheimer’s disease. The findings of these researchers’ subsequent study that was published in 2004 noted that an alcohol extract obtained from muira puama looked after as well as enhanced the capability of the brain cells in mice (partially by means of an antioxidant result), which might prove to be helpful for people who have endured stroke.

Why Rosemary Extract is a good natural antioxidant?

There are lots of excellent antioxidants that combat free radical damage. However, rosemary extract contains more than two dozen antioxidants, and provides potent protection against chronic diseases, including Alzheimer’s, one of the most dreaded diseases of today. It is said that rosemary has been used for thousands of years as a memory enhancer, rosemary extract may well provide a natural, effective, and well-tolerated treatment for dementia.

Why rosemary extract is obviously different? Not only because it’s a antioxidant, but only it has a longer life span of antioxidant activity. Not only that, it contains more than two dozen antioxidants, including carnosic acid, one of the only antioxidants that deactivates free radicals through a multilevel cascade approach.

As the good water solubility and great natural antioxidant activity of rosemary extract and It is widely used in food additives, functional food, spices and daily chemicals.