Pharmacology of Troxerutin

Troxerutin is derived from the Japanese pagoda tree and has been widely used in Western medicine since the 1960s.Troxerutin is a medication used in the treatment of varicose veins and other disorders which cause blood to pool. It is in a class of medications known as flavonoids and works by repairing damage to capillaries and making them less susceptible to subsequent damage.

It can inhibit platelet aggregation, prevent thrombosis, can cure the vascular injury induced by 5 serotonin or bradykinin, increase the capillary resistance, reduce the capillary permeability, prevent edema caused by the increasement of vascular permeability. It has the significant protective effect to acute ischemic brain injury.As the treatment of cerebral thrombosis or the sequela due from the cerebral embolism, such as the hemiplegia, aphasia and myocardial infarction syndrome, arteriosclerosis, central retinitis, phlebitis of thrombosis, varicose veins, edema caused by the vascular permeability rising.

Treatment with troxerutin is administered in a two different phases. In the first phase of treatment, medication is injected either into a vein or a muscle. Alternatively, or sometimes additionally, a patient may be given an oral dose of troxerutin for two to four weeks. Dosing is usually higher at the beginning of treatment and then lowered to maintenance levels once symptoms improve.

After initial treatment with injections or oral medication, patients may be given a topical treatment of troxerutin. The medication is usually suspended in a gel, which is spread on the affected area once or twice daily. This method of administration is quite effective in relieving the symptoms of varicose veins and in reversing the damage to the blood vessels that is caused by the condition.

How Medical Science Concepts Constantly Evolving

Are you aware that the medical science industry is growing everyday? New technology is moving the field forward each and every day. However, most of society doesn’t understand the advanced concepts and introductions that are being made in the field. What is medical science and how exactly is it progressing? The field is really quite complicated and confusing.

You know the doctors and scientists that are researching everyday to make the world a safer and better place? All of these people are closely knitted into the medical treatment field and are constantly looking for ways to improve things. All of these different treatments have been looked at and addressed and through their research, they hope to find a plausible way to improve upon what’s happening today. There are so many different medicines and products in the world, it’s horrible that all of the diseases are still existing and killing millions of people every year. Some problems which attack the human body are presently untreatable. Cancer is just one of the problems that we currently don’t have an answer for. Cancer continues to damage society and hurt the world every year. How can we stop cancer and help protect the world from it’s horrible attack on the human body?

One of the ways we are fighting against diseases and looking for new answers is through the medical science industry. Medical science can be described by the field of study in which we hire well educated people to perform research on the things that are hurting the world. It might be the Earth we live on causing these diseases but if we can work as team to be productive and make the world a better place, then we can end the bad that currently exists.

The technology that exists in the world is only making this process easier. However, with diseases and human attacks constantly changing and altering their course, this is making it difficult. You see, diseases have a way of adapting to the medicines that we have. The horrible reality is that diseases are able to change their course even if we were to develop a cure. If they were to do this, we would be back at the beginning of our struggle. However, technology like medical machines, high definition x-rays and 3d monitoring of body parts inside the body are providing insight about how these things work. Technology is an amazing gift and since we have been blessed with minds capable of creating these items, we’re using them to our advantage. With technology we are taking our research to new heights and levels. Doctors and scientists are constantly collaborating on projects to solve these issues. Within ten years time, analysts suggest that we will have cures for many of the horrible diseases that exist today.

What Are the Medical Uses of Harpagophytum?

The Harpagophytum procumbens plant belongs to the sesame family and grows in South Africa, where natives use the roots to relieve both inflammation and pain. Herbalists also use oral preparations for reducing fevers and treating kidney or liver ailments. The African people combine the roots and tubers into a topical ointment for treating boils, ulcers, and other skin lesions. Other names for the plant include devil’s claw, grapple plant, and wood spider, because of the unusual appendages of the fruit, which attach to passing animals who spread the seeds. Beginning in the 20th century, Europeans returned home with the medicinal plants and used them for appetite restoration and heartburn relief.

Studies indicate Harpagophytum contains harpagoside and beta sitosterol, and research suggests that the medicinal properties of the plant achieve broader results than non-steroidal anti-inflammatory drugs. The plant extract triggers the release of cytokines, proteins that reduce inflammation. Harpagophytum also interferes with the production of cyclo-oxygnase (COX) and lipoxygenase, which contribute to inflammation and swelling. The studies suggest that these plant extracts provide relief similar to COX inhibiting medications. The British Herbal Pharmacopoeia also states that the herb can act as a diuretic, a drug that causes the elimination body fluids, and may also act as a

In Europe, patients use Harpagophytum for the treatment of pain and inflammation associated with arthritis, headaches, and lower back pain. Herbal companies manufacture it in capsule and tablet form. Liquid extracts and topical ointments, containing the active ingredient, harpagoside are also available. Oral forms of the extract provide anywhere between 50 and 100 milligrams of the active ingredient. Physicians do not recommended that the herb be given to children, and health care providers advise against using it before consulting with a professional because of possible medication

Taking Hapragophytum together with aspirin, warfarin or other medications that interfere with blood clotting may cause an increased risk of abnormal bleeding. Some physicians believe the preparation affects blood pressure and heart rate, requiring cautious use in patients with cardiac or circulatory problems. Some reports indicate that the plant can reduce blood sugar, which poses a threat of hypoglycemic reactions in persons using diabetic medications. The active ingredients of the plant may also interfere with the medications commonly prescribed for gastritis or ulcers, as harpagoside typically increases gastric acid

Substances containing Harpagophytum may increase bile production, posing a risk for patients diagnosed with gall bladder disease. The liver breaks down and converts medications, including Harpagophytum. Taking the herb simultaneously with other medications may decrease or increase this metabolic process, affecting the effectiveness of other medications or increasing the likelihood of side

What Are the Medical Uses of Fumaria Officinalis?

Fumaria officinalis, which is also known as fumitory, is a rarely used herb in contemporary alternative medicine. This plant is believed by some North American and European herbalists to possess pain relieving, astringent, detoxifying, bile salt stimulating, laxative, sudorific, diuretic, digestive, liver stimulating, sedative, skin healing and anti-parasitic properties. Nonetheless, some German and French alternative medical practitioners consider the plant to be their medicine of choice for the purification of the blood. Other applications for the Fumaria officinalis include the treatment of acne, poor digestion, eczema, upset stomach, gallbladder conditions, parasitic infection, muscle spasticity, bacterial infection, water retention, constipation, hypothyroidism and sclerosis of the liver.

Fumaria officinalis is rich in pharmacologically active constituents, no single one of which can be considered responsible for all of its medicinal properties. Most research has focused on the isoquinoline alkaloids sinactine, bulbocapnine, sanguinarine, protopine, canadine, N-methylhydrastine, coptisine, fumaritine, corydaline, fumariline, dicentrine, fumaricine, cryptopine, some of which are potentially toxic when administered in high doses.

The results from a preliminary study on the use of Fumaria officinalis alkaloids for the treatment of cardiovascular inflammation and cardiac arrhythmia have been promising, although relatively large doses of protopine and fumoficinaline were required to be effective. A 15-day trial of the herb in diabetic rats found that using the plant resulted in statistically significant reductions in creatinine, blood glucose and cholesterol when compared with the control group.

Fumaria officinalis extracts have also been investigated in the management of the symptoms of psoriasis. The German prescription drug Fumaderm®, used as a treatment for the condition, was developed from a chemical derived from the plant. Monomethyl fumarate is believed to work by inhibiting effects on keratinocyte reproduction and stimulating effects on an anti-inflammatory mediator profile in human white blood cells.

The most promising findings have been in the use of the plant or its extracts for the treatment of various hepatic and hepatobiliary disorders. Several studies have found that chemicals within the plant inhibit hepatic damage and help reduce the blockage of bile ducts. Extremely favorable results have been found with the use of the proprietary formulation Oddibil® in the treatment of biliary dyskinesia and cholecystopathy, with one study finding 80% and 70% improvement in the respoective patient populations. The United States Food and Drug Administration, however, has not made any judgements as to the safety or efficacy of Fumaria officinalis or any of its preparations in the treatment of any medical